Description
Product Characteristics:
Aliases: RNA polymerase I-specific TBP-associated factor 110 kDa antibody, SL1 antibody, Taf1c antibody, TAF1C_HUMAN antibody, TAFI110 antibody, TAFI95 antibody, TATA box binding protein associated factor 1C antibody, TATA box-binding protein-associated factor 1C antibody, TATA box-binding protein-associated factor RNA polymerase I subunit C antibody, TBP associated factor 1C antibody, TBP associated factor RNA polymerase I 95 kDa antibody, TBP associated factor, RNA polymerase I, 110-KD antibody, TBP-associated factor 1C antibody, Transcription initiation factor SL1/TIF-IB subunit C antibody
Target Information: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]